UAMC-3203 hydrochloride

CAS No. 2271358-65-5

UAMC-3203 hydrochloride( —— )

Catalog No. M22389 CAS No. 2271358-65-5

UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 41 In Stock
5MG 65 In Stock
10MG 102 In Stock
25MG 156 In Stock
50MG 192 In Stock
100MG 267 In Stock
200MG 399 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    UAMC-3203 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.
  • Description
    UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Wild type mice derived from a Gpx4 fl/fl breeding Dosage:20 μmol/kg Administration:Injected intraperitoneally; daily, over a period of 4 weeksResult:No toxicity was observed.
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Ferroptosis
  • Recptor
    Ferroptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2271358-65-5
  • Formula Weight
    508.12
  • Molecular Formula
    C25H38ClN5O2S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:50 mg/mL (98.40 mM; Need ultrasonic)
  • SMILES
    Cl.O=S(=O)(NCCN1CCNCC1)c1ccc(NC2CCCCC2)c(NCc2ccccc2)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Devisscher L, et al. Discovery of Novel, Drug-Like Ferroptosis Inhibitors with in Vivo Efficacy. J Med Chem. 2018 Nov 21;61(22):10126-10140.
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